MCM8 Antibody (1F9)

Novus Biologicals, part of Bio-Techne | Catalog # H00084515-M02

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Sandwich ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1F9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MCM8 Antibodies »

Product Specifications

Immunogen

MCM8 (AAH08830, 646 a.a. ~ 735 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TYSDEFGNLDFERSQHGSGMSNRSTAKRFISALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM

Reactivity Notes

Human. Other species not tested.

Specificity

MCM8 - MCM8 minichromosome maintenance deficient 8 (S. cerevisiae)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for MCM8 Antibody (1F9)

Sandwich ELISA: MCM8 Antibody (1F9) [H00084515-M02] - Detection limit for recombinant GST tagged MCM8 is 0.03 ng/ml as a capture antibody.

Applications for MCM8 Antibody (1F9)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MCM8

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternate Names

C20orf154, chromosome 20 open reading frame 154, dJ967N21.5, DNA replication licensing factor MCM8, MCM8 minichromosome maintenance deficient 8, MGC119522, MGC119523, MGC12866, MGC4816, Minichromosome maintenance 8, minichromosome maintenance complex component 8, REC, REC homolog

Entrez Gene IDs

84515 (Human)

Gene Symbol

MCM8

OMIM

608187 (Human)

UniProt

AAH08830 (Human)

Additional MCM8 Products

Product Documents for MCM8 Antibody (1F9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MCM8 Antibody (1F9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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