MCT2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87846

Novus Biologicals, part of Bio-Techne
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NBP1-87846
NBP1-87846-25ul
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MCT2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MCT2 Antibody

Western Blot: MCT2 Antibody [NBP1-87846]

Western Blot: MCT2 Antibody [NBP1-87846]

Western Blot: MCT2 Antibody [NBP1-87846] - Analysis in control (vector only transfected HEK293T lysate) and SLC16A7 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: MCT2 Antibody [NBP1-87846]

Immunohistochemistry-Paraffin: MCT2 Antibody [NBP1-87846]

Immunohistochemistry-Paraffin: MCT2 Antibody [NBP1-87846] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuronal cells.

Applications for MCT2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MCT2

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family 16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. MCT2 is a high affinity transporter that catalyzes the rapid transport of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate across the plasma membrane.

Long Name

Monocarboxylate transporter 2

Alternate Names

MCT 2, SLC16A7

Gene Symbol

SLC16A7

Additional MCT2 Products

Product Documents for MCT2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MCT2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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