MDA5 Antibody [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76761CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-76761AF350

Alexa Fluor 405

NBP1-76761AF405

Alexa Fluor 488

NBP1-76761AF488

Alexa Fluor 532

NBP1-76761AF532

Alexa Fluor 594

NBP1-76761AF594

Alexa Fluor 647

NBP1-76761AF647

Alexa Fluor 700

NBP1-76761AF700

Alexa Fluor 750

NBP1-76761AF750

Biotin

NBP1-76761B

DyLight 350

NBP1-76761UV

DyLight 405

NBP1-76761V

DyLight 488

NBP1-76761G

DyLight 550

NBP1-76761R

DyLight 594

NBP1-76761DL594

DyLight 650

NBP1-76761C

DyLight 680

NBP1-76761FR

DyLight 755

NBP1-76761IR

FITC

NBP1-76761F

HRP

NBP1-76761H

Janelia Fluor 525

NBP1-76761JF525

Janelia Fluor 549

NBP1-76761JF549

Janelia Fluor 585

NBP1-76761JF585

Janelia Fluor 635

NBP1-76761JF635

Janelia Fluor 646

NBP1-76761JF646

Janelia Fluor 669

NBP1-76761JF669

mFluor Violet 450 SE

NBP1-76761MFV450

mFluor Violet 500 SE

NBP1-76761MFV500

mFluor Violet 610 SE

NBP1-76761MFV610

PerCP

NBP1-76761PCP

Forumulation

Catalog #

BSA Free

NBP1-76761

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

CoraFluor 1

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IFIH1/MDA5 Antibodies »

Product Summary for MDA5 Antibody [CoraFluor™ 1]

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the center of human MDA5. The immunogen is located within amino acids 330 - 380 of MDA5. Amino Acid Squence: AKDHLDKKKKASEPGK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for MDA5 Antibody [CoraFluor™ 1]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: IFIH1/MDA5

Gene ID: 64135 DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.

Long Name

Melanoma Differentiation-Associated Protein 5

Alternate Names

AGS7, Helicard, Hlcd, IDDM19, IFIH1, IMD95, MDA-5, RH116, SGMRT1

Gene Symbol

IFIH1

Additional IFIH1/MDA5 Products

Product Documents for MDA5 Antibody [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MDA5 Antibody [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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