MDR1/ABCB1 Antibody (MDR1/8986R) [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24231H

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Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-23782

Alexa Fluor 350

NBP3-24231AF350

Alexa Fluor 405

NBP3-24231AF405

Alexa Fluor 488

NBP3-24231AF488

Alexa Fluor 532

NBP3-24231AF532

Alexa Fluor 594

NBP3-24231AF594

Alexa Fluor 647

NBP3-24231AF647

Alexa Fluor 700

NBP3-24231AF700

Alexa Fluor 750

NBP3-24231AF750

Allophycocyanin

NBP3-24231APC

Biotin

NBP3-24231B

CoraFluor 1

NBP3-24231CL1

DyLight 350

NBP3-24231UV

DyLight 405

NBP3-24231V

DyLight 488

NBP3-24231G

DyLight 550

NBP3-24231R

DyLight 594

NBP3-24231DL594

DyLight 650

NBP3-24231C

DyLight 680

NBP3-24231FR

DyLight 755

NBP3-24231IR

FITC

NBP3-24231F

Janelia Fluor 525

NBP3-24231JF525

Janelia Fluor 549

NBP3-24231JF549

Janelia Fluor 646

NBP3-24231JF646

Janelia Fluor 669

NBP3-24231JF669

mFluor Violet 450 SE

NBP3-24231MFV450

mFluor Violet 500 SE

NBP3-24231MFV500

mFluor Violet 610 SE

NBP3-24231MFV610

PE

NBP3-24231PE

PerCP

NBP3-24231PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-24231

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

HRP

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # MDR1/8986R

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MDR1/ABCB1 Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa500-700) of human MDR1/ABCB1 protein (exact sequence is proprietary)

Localization

Membrane.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for MDR1/ABCB1 Antibody (MDR1/8986R) [HRP]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MDR1/ABCB1

MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). MDR1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. (provided by RefSeq)

Long Name

ATP-binding Cassette, Sub-family B (MDR/TAP), Member 1B

Alternate Names

ABC20, ABCB1, ABCB1B, CD243, CLCS, GP170, IBD13, PGY1

Gene Symbol

ABCB1

Additional MDR1/ABCB1 Products

Product Documents for MDR1/ABCB1 Antibody (MDR1/8986R) [HRP]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MDR1/ABCB1 Antibody (MDR1/8986R) [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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