Melan-A/MART-1 Antibody (MLANA/1761R) [DyLight 594]

DyLight 594 (Excitation = 593 nm, Emission = 618 nm)

Recombinant Monoclonal Rabbit IgG Clone # MLANA/1761R

Please see the vial label for concentration. If unlisted please contact technical services.

Recombinant human full-length Melan-A/MART-1 protein (Uniprot: Q16655)

Cytoplasmic

This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Melanoma Marker

Monoclonal

Rabbit

IgG

Protein A purified

50mM Sodium Borate

0.05% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C in the dark.