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Melanocortin-2 R/MC2R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-93419

Novus Biologicals, part of Bio-Techne
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NB100-93419

Key Product Details

Species Reactivity

Validated:

Human, Fish

Cited:

Fish

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence ENINNTARNNSDC corresponding to N-Terminus according to NP_000520.1.

Epitope

ENINNTARNNSDC

Reactivity Notes

Fish reactivity reported in scientific literature (PMID: 28837788).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Melanocortin-2 R/MC2R Antibody

Western Blot: Melanocortin-2 R/MC2R Antibody [NB100-93419]

Western Blot: Melanocortin-2 R/MC2R Antibody [NB100-93419]

Western Blot: MC2 Receptor Antibody [NB100-93419] - (1ug/ml) staining of Human Skin lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Melanocortin-2 R/MC2R Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 40 kDa band observed in human skin lysates is reported in scientific literature (PMID: 16497811). Use in Immunohistochemistry-paraffin reported in scientific literature (PMID: 28837788).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Melanocortin-2 R/MC2R

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. [provided by RefSeq]

Long Name

Melanocortin 2 Receptor

Alternate Names

ACTHR, MC2R, Melanocortin-2R, Melanocortin2R

Entrez Gene IDs

4158 (Human)

Gene Symbol

MC2R

Additional Melanocortin-2 R/MC2R Products

Product Documents for Melanocortin-2 R/MC2R Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Melanocortin-2 R/MC2R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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