Mer Antibody (MERTK/3023) [DyLight 650]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14234C

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-13838

Alexa Fluor 350

NBP3-14234AF350

Alexa Fluor 405

NBP3-14234AF405

Alexa Fluor 488

NBP3-14234AF488

Alexa Fluor 532

NBP3-14234AF532

Alexa Fluor 594

NBP3-14234AF594

Alexa Fluor 647

NBP3-14234AF647

Alexa Fluor 700

NBP3-14234AF700

Alexa Fluor 750

NBP3-14234AF750

Allophycocyanin

NBP3-14234APC

Biotin

NBP3-14234B

CoraFluor 1

NBP3-14234CL1

DyLight 350

NBP3-14234UV

DyLight 405

NBP3-14234V

DyLight 488

NBP3-14234G

DyLight 550

NBP3-14234R

DyLight 594

NBP3-14234DL594

DyLight 680

NBP3-14234FR

DyLight 755

NBP3-14234IR

FITC

NBP3-14234F

HRP

NBP3-14234H

Janelia Fluor 525

NBP3-14234JF525

Janelia Fluor 549

NBP3-14234JF549

Janelia Fluor 585

NBP3-14234JF585

Janelia Fluor 635

NBP3-14234JF635

Janelia Fluor 646

NBP3-14234JF646

Janelia Fluor 669

NBP3-14234JF669

PE

NBP3-14234PE

PerCP

NBP3-14234PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-14234

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin, Protein Array

Label

DyLight 650 (Excitation = 652 nm, Emission = 672 nm)

Antibody Source

Monoclonal Mouse IgG_2A Clone # MERTK/3023

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Mer Antibodies »

Product Summary for Mer Antibody (MERTK/3023) [DyLight 650]

Immunogen

Recombinant human Mer protein fragment (around aa 55-148) (exact sequence is proprietary) (Uniprot: Q12866)

Reactivity Notes

Others not known.

Localization

Cell surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Applications for Mer Antibody (MERTK/3023) [DyLight 650]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Protein Array

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Mer

MerTK (c-mer, Nyk, Eyk) is a tyrosine kinase that belongs to a family of transmembrane receptors (1). MerTk has been implicated in reversible cell growth arrest, survival, proliferation and cell adhesion. Growth arrest specific protein 6 (Gas6) is an activating ligand for MerTK (2-3). MerTK is required for clearance of apoptotic cells by mononuclear phagocytes in mice; with its absence resulting in progressive lupus like autoimmunity (4). Defects in MERTK are a cause of retinitis pigmentosa (RP) (5).

Long Name

Receptor Tyrosine Protein Kinase Mer

Alternate Names

c-Eyk, C-mer, MerTK

Gene Symbol

MERTK

Additional Mer Products

Product Documents for Mer Antibody (MERTK/3023) [DyLight 650]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Mer Antibody (MERTK/3023) [DyLight 650]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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