Mesothelin Antibody (SR2132) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21887

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21887-100ul
NBP3-21887-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2132

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Mesothelin Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Mesothelin (Uniprot #: Q13421)

Specificity

Detects endogenous levels of total Mesothelin

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Mesothelin Antibody (SR2132) - BSA Free

Western Blot: Mesothelin Antibody (SR2132) [NBP3-21887] -

Western Blot: Mesothelin Antibody (SR2132) [NBP3-21887] - Western blot analysis using NBP3-21887 in HeLa cell lysate.

Applications for Mesothelin Antibody (SR2132) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:100-1:500

Immunoprecipitation

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mesothelin

MSLN, also known as Mesothelin, has 4 isoforms, a 630 amino acid isoform that is 69 kDa, a 622 amino acid isoform that is 68 kDa, a 656 amino acid isoform that is 71 kDa, and a 621 amino acid isoform that is 68 kDa, expressed in lung, heart, placenta kidney, and overexpressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas. Membrane-anchored forms may play a role in cellular adhesion and megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro. Current research is being performed on several diseases and disorders including squamous cell carcinoma, ovarian cancer, carcinoma, malignant biphasic mesothelioma, bile duct adenoma, malignant mesothelioma, malignant pleural mesothelioma, gastrointestinal stromal tumor, renal clear cell carcinoma, epithelioid sarcoma, benign mesothelioma, pancreatic ductal adenocarcinoma, asbestosis, pancreatic ductal carcinoma, thymic carcinoma, acute myeloid leukemia, epithelial ovarian cancer, myeloid leukemia, thoracic cancer, and pancreatitis. This protein has also shown an interaction with MUC16 and RSG1 in cell adhesion and pancreas development processes and pathways.

Alternate Names

CAK1, MPF, MSLN, SMR

Gene Symbol

MSLN

Additional Mesothelin Products

Product Documents for Mesothelin Antibody (SR2132) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Mesothelin Antibody (SR2132) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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