mGluR3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31109

Novus Biologicals, part of Bio-Techne
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NBP1-31109
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all mGluR3 Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human mGluR3. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Zebrafish (87%).

Localization

Cell membrane, Multi-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

99 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for mGluR3 Antibody

Western Blot: mGluR3 Antibody [NBP1-31109]

Western Blot: mGluR3 Antibody [NBP1-31109]

Western Blot: mGluR3 Antibody [NBP1-31109] - Various tissue extracts (50 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with mGluR3 antibody [C3], C-term (NBP1-31109). The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: mGluR3 Antibody [NBP1-31109]

Immunocytochemistry/ Immunofluorescence: mGluR3 Antibody [NBP1-31109]

Immunocytochemistry/Immunofluorescence: mGluR3 Antibody [NBP1-31109] - mGluR3 antibody [C3], C-term detects mGluR3 protein by immunofluorescent analysis.Sample: DIV9 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: mGluR3 stained by mGluR3 antibody [C3], C-term (NBP1-31109).Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody.Blue: Fluoroshield with DAPI.
Western Blot: mGluR3 Antibody [NBP1-31109]

Western Blot: mGluR3 Antibody [NBP1-31109]

Western Blot: mGluR3 Antibody [NBP1-31109] - (30 ug of whole cell lysate) A: 293T B: A431 7. 5% SDS PAGE, antibody diluted at 1:500.

Applications for mGluR3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100 - 1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: mGluR3

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Long Name

Metabotropic Glutamate Receptor 3

Alternate Names

GPRC1C, GRM3

Entrez Gene IDs

2913 (Human)

Gene Symbol

GRM3

UniProt

Q14832

Additional mGluR3 Products

Product Documents for mGluR3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for mGluR3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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