MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.

Alternate Names

class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM

Gene Symbol

HLA-DMA

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Product Documents for MHC Class II Antibody (CVS20) [Janelia Fluor® 635]

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Product Specific Notices for MHC Class II Antibody (CVS20) [Janelia Fluor® 635]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MHC Class II Antibody (CVS20) [Janelia Fluor® 635]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34848JF635

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Product Summary for MHC Class II Antibody (CVS20) [Janelia Fluor® 635]

Immunogen

Clonality

Host

Isotype

Applications for MHC Class II Antibody (CVS20) [Janelia Fluor® 635]

Flow Cytometry

Immunohistochemistry

Immunohistochemistry-Frozen

Immunoprecipitation

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Background: MHC Class II

Alternate Names

Gene Symbol

Additional MHC Class II Products

Product Documents for MHC Class II Antibody (CVS20) [Janelia Fluor® 635]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for MHC Class II Antibody (CVS20) [Janelia Fluor® 635]

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