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Mind Bomb 2/MIB2 Antibody (3A7)

Novus Biologicals, part of Bio-Techne | Catalog # H00142678-M02

Novus Biologicals, part of Bio-Techne
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H00142678-M02

Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 3A7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

MIB2 (AAH37542, 381 a.a. ~ 480 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. IGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCLVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRL

Specificity

MIB2 - mindbomb homolog 2 (Drosophila) (3A7)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for Mind Bomb 2/MIB2 Antibody (3A7)

Sandwich ELISA: Mind Bomb 2/MIB2 Antibody (3A7) [H00142678-M02] - Detection limit for recombinant GST tagged MIB2 is approximately 0.1ng/ml as a capture antibody.

Applications for Mind Bomb 2/MIB2 Antibody (3A7)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Sandwich ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This product is useful for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Mind Bomb 2/MIB2

MIB2/Skeletrophin is an actin-binding protein that bears two MIB/HERC2 domains, a ZZ-type zinc-finger domain, nine ankyrin repeats, and two RING-finger domains. The C-terminal RING domain has been found to have E3 ubiquitin ligase activity that mediates ubiquitination of the intracellular regions of the Notch receptor and its ligands to regulate Notch signaling. MIB2/Skeletrophin appears to be important to muscle development and may function as a suppressor of melanoma invasion.

Long Name

Mindbomb Homolog 2

Alternate Names

MIB2, Mind Bomb-2, Novelzin, SKD, Skeletrophin, ZZANK1, ZZZ5

Entrez Gene IDs

142678 (Human)

Gene Symbol

MIB2

Additional Mind Bomb 2/MIB2 Products

Product Documents for Mind Bomb 2/MIB2 Antibody (3A7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mind Bomb 2/MIB2 Antibody (3A7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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