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Mitofusin 2 Antibody (6A8)

Novus Biologicals, part of Bio-Techne | Catalog # H00009927-M01

Novus Biologicals, part of Bio-Techne
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H00009927-M01

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 6A8

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

MFN2 (NP_055689, 661 a.a. ~ 757 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKKIEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR

Specificity

MFN2 (6A8)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for Mitofusin 2 Antibody (6A8)

Western Blot: Mitofusin 2 Antibody (6A8) [H00009927-M01]

Western Blot: Mitofusin 2 Antibody (6A8) [H00009927-M01]

Western Blot: Mitofusin 2 Antibody (6A8) [H00009927-M01] - MFN2 monoclonal antibody (M01), clone 6A8. Analysis of MFN2 expression in PC-12.
Immunohistochemistry-Paraffin: Mitofusin 2 Antibody (6A8) [H00009927-M01]

Immunohistochemistry-Paraffin: Mitofusin 2 Antibody (6A8) [H00009927-M01]

Immunohistochemistry-Paraffin: Mitofusin 2 Antibody (6A8) [H00009927-M01] - Analysis of monoclonal antibody to MFN2 on formalin-fixed paraffin-embedded human kidney. Antibody concentration 3 ug/ml.
Western Blot: Mitofusin 2 Antibody (6A8) [H00009927-M01]

Western Blot: Mitofusin 2 Antibody (6A8) [H00009927-M01]

Western Blot: Mitofusin 2 Antibody (6A8) [H00009927-M01] - MFN2 monoclonal antibody (M01), clone 6A8. Analysis of MFN2 expression in HeLa.

Applications for Mitofusin 2 Antibody (6A8)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Mitofusin 2

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Alternate Names

CMT2A, CMT2A2, CPRP1, HSG, MARF, MFN2

Entrez Gene IDs

9927 (Human)

Gene Symbol

MFN2

OMIM

608507 (Human)

Additional Mitofusin 2 Products

Product Documents for Mitofusin 2 Antibody (6A8)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mitofusin 2 Antibody (6A8)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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