Mitofusin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85477

Novus Biologicals, part of Bio-Techne
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NBP1-85477-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Predicted:

Mouse (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Mitofusin 2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIKQITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSDRCSTAITNSLQTMQQD

Reactivity Notes

Reactivity reported in scientific literature (PMID: 24013556).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Mitofusin 2 Antibody

Immunohistochemistry-Paraffin: Mitofusin 2 Antibody [NBP1-85477]

Immunohistochemistry-Paraffin: Mitofusin 2 Antibody [NBP1-85477]

Immunohistochemistry-Paraffin: Mitofusin 2 Antibody [NBP1-85477] - Staining of human small intestine shows strong positivity in lymphoid cells.
Immunohistochemistry-Paraffin: Mitofusin 2 Antibody [NBP1-85477]

Immunohistochemistry-Paraffin: Mitofusin 2 Antibody [NBP1-85477]

Immunohistochemistry-Paraffin: Mitofusin 2 Antibody [NBP1-85477] - Staining of human heart muscle shows moderate cytoplasmic positivity in myocytes.
Immunohistochemistry-Paraffin: Mitofusin 2 Antibody [NBP1-85477]

Immunohistochemistry-Paraffin: Mitofusin 2 Antibody [NBP1-85477]

Immunohistochemistry-Paraffin: Mitofusin 2 Antibody [NBP1-85477] - Staining of human cerebral cortex shows strong positivity in neurons.
View 1 more images

Applications for Mitofusin 2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mitofusin 2

MFN2 encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Alternate Names

CMT2A, CMT2A2, CPRP1, HSG, MARF, MFN2

Gene Symbol

MFN2

Additional Mitofusin 2 Products

Product Documents for Mitofusin 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Mitofusin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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