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MMP-10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-17309

Novus Biologicals, part of Bio-Techne
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NBP2-17309

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for MMP-10 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human MMP-10. The exact sequence is proprietary.

Reactivity Notes

Mouse (82%), Rat (80%).

Localization

Secreted; extracellular space; extracellular matrix

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MMP-10 Antibody

Western Blot: MMP-10 Antibody [NBP2-17309]

Western Blot: MMP-10 Antibody [NBP2-17309]

Western Blot: MMP-10 Antibody [NBP2-17309] - HepG2 whole cell extract and conditioned medium (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with MMP10 antibody [N1C1] diluted at 1:1000.
Immunohistochemistry-Paraffin: MMP-10 Antibody [NBP2-17309]

Immunohistochemistry-Paraffin: MMP-10 Antibody [NBP2-17309]

Immunohistochemistry-Paraffin: MMP10 Antibody [NBP2-17309] - Immunohistochemical analysis of paraffin-embedded Gastric ca, using antibody at 1:500 dilution.
Western Blot: MMP-10 Antibody [NBP2-17309]

Western Blot: MMP-10 Antibody [NBP2-17309]

Western Blot: MMP-10 Antibody [NBP2-17309] - Non-transfected (-) and MMP10-transfected (+) 293T whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with MMP10 antibody diluted at 1:5000.

Applications for MMP-10 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MMP-10

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]

Long Name

Matrix Metalloproteinase 10

Alternate Names

MMP10, Stromelysin 2

Gene Symbol

MMP10

UniProt

Additional MMP-10 Products

Product Documents for MMP-10 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MMP-10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.