MMP-16/MT3-MMP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33102

Novus Biologicals, part of Bio-Techne
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NBP1-33102
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (98%), Chicken (98%), Xenopus (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MMP-16/MT3-MMP Antibodies »

Product Summary for MMP-16/MT3-MMP Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human MMP-16/MT3-MMP. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (92%), Japanese Medaka (83%).

Localization

Isoform Long: Cell membrane, Single-pass type I membrane protein, Extracellular side (Potential), Isoform Short: Secreted, extracellular space, extracellular matrix, Cell surface

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MMP-16/MT3-MMP Antibody

Western Blot: MMP-16/MT3-MMP Antibody [NBP1-33102]

Western Blot: MMP-16/MT3-MMP Antibody [NBP1-33102]

Western Blot: MMP-16/MT3-MMP Antibody [NBP1-33102] - A. 50 ug rat kidney lysate/extract 10 % SDS-PAGEMMP16 antibody dilution: 1:1000
Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-33102]

Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-33102]

Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-33102] - A549 xenograft , using MMP16 antibody at 1:100 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.
Western Blot: MMP-16/MT3-MMP Antibody [NBP1-33102]

Western Blot: MMP-16/MT3-MMP Antibody [NBP1-33102]

Western Blot: MMP-16/MT3-MMP Antibody [NBP1-33102] - (30 ug of whole cell lysate) Hep G2 10% SDS PAGE, antibody diluted at 1:1000.
View 1 more images

Applications for MMP-16/MT3-MMP Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MMP-16/MT3-MMP

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.

Long Name

Matrix Metalloproteinase 16/Membrane Type 3 MMP

Alternate Names

MMP16, MT3-MMP

Gene Symbol

MMP16

Additional MMP-16/MT3-MMP Products

Product Documents for MMP-16/MT3-MMP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MMP-16/MT3-MMP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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