MMP-16/MT3-MMP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86721

Novus Biologicals, part of Bio-Techne
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NBP1-86721
NBP1-86721-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MMP-16/MT3-MMP Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TTLQPGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITVWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMGCD

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23435261)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MMP-16/MT3-MMP Antibody

Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-86721]

Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-86721]

Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-86721] - Staining of human cerebral cortex shows weak cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-86721]

Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-86721]

Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-86721] - Staining of human hippocampus shows moderate cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-86721]

Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-86721]

Immunohistochemistry-Paraffin: MMP-16/MT3-MMP Antibody [NBP1-86721] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.

Applications for MMP-16/MT3-MMP Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MMP-16/MT3-MMP

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.

Long Name

Matrix Metalloproteinase 16/Membrane Type 3 MMP

Alternate Names

MMP16, MT3-MMP

Gene Symbol

MMP16

Additional MMP-16/MT3-MMP Products

Product Documents for MMP-16/MT3-MMP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MMP-16/MT3-MMP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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