MOG Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB300-948

Novus Biologicals, part of Bio-Techne
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NB300-948
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Key Product Details

Species Reactivity

Validated:

Human, Porcine

Cited:

Porcine

Predicted:

Bovine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Validated:

Peptide ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all MOG Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-AGQFLEELRNPF corresponding to C-Terminus according to NP_996532.2, NP_996535.2, NP_001008229.1.

Reactivity Notes

Use in Porcine reported in scientific literature (PMID:35027884) .

Specificity

This antibody is expected to recognise NP_996532.2 (isf a1), NP_996535.2 (isf a2) and NP_001008229.1 (isf a3)

Marker

Oligodendrocyte Marker

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for MOG Antibody

Western Blot: MOG Antibody [NB300-948]

Western Blot: MOG Antibody [NB300-948]

Western Blot: MOG Antibody [NB300-948] - (0.03ug/ml) staining of Human Amygdala lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.

Applications for MOG Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

0.03 - 1 ug/ml
Application Notes
Western Blot: Approx 26kDa band observed in Human Brain lysates (calculated MW of 25.4kDa according to NP_001008229.1). Recommended concentration: 0.03-0.1ug/ml. Primary incubation was for 1 hour.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MOG

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Long Name

Myelin Oligodendrocyte Glycoprotein

Alternate Names

MGC26137, MOG Ig-AluB, MOGIG2, myelin oligodendrocyte glycoprotein, myelin-oligodendrocyte glycoprotein

Entrez Gene IDs

4340 (Human); 17441 (Mouse); 24558 (Rat)

Gene Symbol

MOG

UniProt

NP_002424

Additional MOG Products

Product Documents for MOG Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MOG Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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