Mouse C1q R1/CD93 APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB1696A
Discontinued Product
FAB1696A has been discontinued.
View all C1qR1/CD93 products.
Key Product Details
Species Reactivity
Mouse
Applications
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Rat IgG2B Clone # 223437
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse C1q R1/CD93
Ala23-Asn572
Accession # O89103
Ala23-Asn572
Accession # O89103
Specificity
Detects mouse C1q R1/CD93 in direct ELISAs.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Scientific Data Images for Mouse C1q R1/CD93 APC-conjugated Antibody
Detection of C1q R1/CD93 in bEnd.3 Mouse Cell Line by Flow Cytometry.
bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse C1q R1/CD93 APC-conjugated Monoclonal Antibody (Catalog # FAB1696A, filled histogram) or isotype control antibody (Catalog # IC013A, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Mouse C1q R1/CD93 APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: bEnd.3 mouse endothelioma cell line
Sample: bEnd.3 mouse endothelioma cell line
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: C1qR1/CD93
Complement component 1, q subcomponent receptor (C1q R1), also known as C1q Rp, Collectin receptor and AA4 antigen in rodents, mediates enhanced phagocytosis by monocytes and macrophages upon interaction with soluble defense collagens including C1q, MBL (mannose-binding lectin) and SP-A (pulmonary surfactant protein A) (1, 2). It is a type I transmembrane glycoprotein expressed on endothelial cells, hematopoietic progenitor cells, platelets and cells of myeloid origin. C1q R1 has also been identified as a stem cell marker (3, 4).
References
- Kim, T.S. et al. (2000) Mol. Immunol. 37:377.
- Dean, Y.D. et al. (2001) Eur. J. Immunol. 31:1370.
- Petrenko, O. et al. (1999) Immunity 10:691.
- Danet, G.H. et al. (2002) Proc. Natl. Acad. Sci. USA 99:1044.
Long Name
Complement Component C1q Receptor
Alternate Names
AA4 Antigen, C1q R1, C1q Rp, C1qRp, CD93, Collectin Receptor, Ly68
Gene Symbol
CD93
UniProt
Additional C1qR1/CD93 Products
Product Documents for Mouse C1q R1/CD93 APC-conjugated Antibody
Product Specific Notices for Mouse C1q R1/CD93 APC-conjugated Antibody
For research use only
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