Mouse CD200 R3 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB6554P

R&D Systems, part of Bio-Techne
Discontinued Product
FAB6554P has been discontinued. View all CD200 R3 products.

Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Polyclonal Sheep IgG

View all CD200 R3 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse CD200 R3
Ser26-Ser245
Accession # Q5UKY4

Specificity

Detects mouse CD200 R3 in flow cytometry.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Scientific Data Images for Mouse CD200 R3 PE-conjugated Antibody

Detection of CD200 R3 antibody in MC/9-2 Mouse Cell Line antibody by Flow Cytometry.

Detection of CD200 R3 in MC/9‑2 Mouse Cell Line by Flow Cytometry.

MC/9-2 mouse mast cell line was stained with Sheep Anti-Mouse CD200 R3 PE-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB6554P, filled histogram) or isotype control antibody (Catalog # IC016P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Mouse CD200 R3 PE-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: MC/9‑2 mouse mast cell line

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: CD200 R3

Mouse CD200 R3, also known as CD200RLb, is a 38-40 kDa type I transmembrane glycoprotein member of a small family of CD200R-related molecules. Family members named CD200R1-5 represent activating counterparts to CD200R that is a widely expressed inhibitory receptor for the ligand CD200. Consistent with other family members, CD200 R3 is a Ig-superfamily member with a V-type and C2-type Ig-like domain. But unlike other family members, it presents as a disulfide-linked homodimer that is highly spliced, poorly glycosylated, and shows an unusual modification of its C2-type Ig-like domain. It is expressed by mast cells, basophils, and CD49+ regulatory dendritic cells. It does not bind CD200. When experimentally activated, it induces IL-4 production and degranulation. There is no direct human or rat counterpart to mouse CD200 R3.

Long Name

CD200 Receptor 3

Alternate Names

CD200R3, CD200RLb

Entrez Gene IDs

74603 (Mouse)

Gene Symbol

CD200R3

UniProt

Q5UKY4 (Mouse)

Additional CD200 R3 Products

Product Documents for Mouse CD200 R3 PE-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse CD200 R3 PE-conjugated Antibody

For research use only

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