Mouse CXCR1/IL-8RA PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB8628P

Recombinant Monoclonal Antibody.
R&D Systems, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry, Western Blot

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1122A

View all CXCR1/IL-8RA Antibodies »

Product Specifications

Immunogen

A peptide corresponding to the N-terminal amino acid sequence of mouse CXCR1
Accession # NP_839972

Specificity

Detects mouse CXCR1 transfectants but not CXCR2 transfectants in flow cytometry.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Mouse CXCR1/IL-8RA PE-conjugated Antibody

Detection of CXCR1/IL-8 RA antibody in HEK293 Human Cell Line Transfected with Mouse CXCR1/IL-8 RA and eGFP antibody by Flow Cytometry.

Detection of CXCR1/IL‑8 RA in HEK293 Human Cell Line Transfected with Mouse CXCR1/IL-8 RA and eGFP by Flow Cytometry.

HEK293 human embryonic kidney cell line transfected with either (A) mouse CXCR1/IL-8 RA or (B) mouse CXCR2/IL-8 RB and eGFP was stained with Rabbit Anti-Mouse CXCR1/IL-8 RA PE-conjugated Monoclonal Antibody (Catalog # FAB8628P). Quadrant markers were set based on control antibody staining (Catalog # IC105P). View our protocol for Staining Membrane-associated Proteins.

Applications for Mouse CXCR1/IL-8RA PE-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: HEK293 human embryonic kidney cell line transfected with mouse CXCR1/IL-8 RA

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CXCR1/IL-8RA

CXCR1 is a G protein-linked seven transmembrane domain spanning chemokine receptor that binds to mouse GCP-2, which is a powerful chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. The chemokine receptors CXCR1 and CXCR2 play an important role in mediating neutrophil recruitment and neutrophil-dependent injury in several models of inflammation.

Long Name

Interleukin 8 Receptor A

Alternate Names

CD181, IL-8 RA, IL8RA

Entrez Gene IDs

3577 (Human); 227288 (Mouse); 54258 (Rat)

Gene Symbol

CXCR1

UniProt

NP_839972

Additional CXCR1/IL-8RA Products

Product Documents for Mouse CXCR1/IL-8RA PE-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse CXCR1/IL-8RA PE-conjugated Antibody

For research use only

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