Mouse IL-16 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB1727
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2B Clone # 228109
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-16
Ser1205-Ser1322
Accession # O54824
Ser1205-Ser1322
Accession # O54824
Specificity
Detects mouse IL-16 in direct ELISAs and Western blots. Shows approximately 50% cross‑reactivity with recombinant human (rh) IL-16 and no cross-reactivity with rmC-10, rhI-309, rhHCC-4, or rhHCC-1.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Applications for Mouse IL-16 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Mouse IL-16
Sample: Recombinant Mouse IL-16
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IL-16
Interleukin 16 (IL-16), also known as lymphocyte chemoattractant factor (LCF), refers to the C-terminal peptide of pro-IL-16 isoform 1, which is a nuclear and cytoplasmic PDZ-containing protein. The C-terminus of pro-IL-16 is cleaved by Caspase-3, resulting in the release of secreted IL-16. Mature IL-16 has been shown to bind the cell surface receptor CD4 and functions as an immunomodulatory cytokine.
Long Name
Interleukin 16
Alternate Names
IL16, LCF
Gene Symbol
IL16
UniProt
Additional IL-16 Products
Product Documents for Mouse IL-16 Antibody
Product Specific Notices for Mouse IL-16 Antibody
For research use only
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