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Mouse OCIL/CLEC2d Antibody

R&D Systems, part of Bio-Techne | Catalog # AF3376

R&D Systems, part of Bio-Techne
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AF3376
AF3376-SP

Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

E. coli-derived recombinant mouse OCIL/CLEC2d
Ala65-Ser207
Accession # Q91V08

Specificity

Detects mouse OCIL/CLEC2d in direct ELISAs and Western blots. In Western blots, approximately 35% cross-reactivity with recombinant mouse OCILRP2 is observed and less than 2% cross-reactivity with recombinant human OCIL is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse OCIL/CLEC2d Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse OCIL/CLEC2d

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: OCIL/CLEC2d

Mouse OCIL, also known as C-type lectin-related b (Clrb), is a type II transmembrane protein belonging to the natural killer (NK) cell receptor group of the C-type lectin superfamily. It is found on hematopoietic cells, osteoclasts and chondrocytes. OCIL preferentially binds high molecular weight, sulfated glycosaminoglycans and is a ligand for the mouse NK R-PIB/D receptor. OCIL blocks osteoclast differentiation. Engagement of OCIL with NK R-PIB/D on NK cells inhibits NK cell functions. The extracellular domain of mouse OCIL shares 49% and 71% amino acid sequence identity with rat and human OCIL, respectively.

Long Name

Osteoclast Inhibitory Lectin

Alternate Names

CLEC2D, LLT1

Entrez Gene IDs

29121 (Human); 93694 (Mouse)

Gene Symbol

CLEC2D

UniProt

Additional OCIL/CLEC2d Products

Product Documents for Mouse OCIL/CLEC2d Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse OCIL/CLEC2d Antibody

For research use only

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