Mouse TGF-beta RI/ALK-5 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB587
Key Product Details
Species Reactivity
Validated:
Mouse
Cited:
Human, Mouse
Applications
Validated:
Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2A Clone # 141229
Product Specifications
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TGF‑ beta RI/ALK-5
Ala21-Glu121
Accession # BAA05023
Ala21-Glu121
Accession # BAA05023
Specificity
Detects mouse TGF‑ beta RI/ALK-5 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows approximately 20‑25% cross-reactivity with recombinant human (rh) TGF-beta RI and no cross-reactivity with recombinant rat MIS RII, rhTGF-beta RII, rhTGF‑ beta RIIb, or rhTGF‑ beta RIII.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Mouse TGF-beta RI/ALK-5 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera (Catalog # 587-RI)
Sample: Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera (Catalog # 587-RI)
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: TGF-beta RI/ALK-5
References
- Miyazono, K. et al. (1994) Adv. In Immunol. 55:181.
- Massagùe, J. (1998) Ann. Rev. Biochem. 67:753.
Long Name
Transforming Growth Factor beta Receptor I
Alternate Names
ALK-5, SKR4, TGF-bRI, TGFbetaRI, TGFBR1
Gene Symbol
TGFBR1
UniProt
Additional TGF-beta RI/ALK-5 Products
Product Documents for Mouse TGF-beta RI/ALK-5 Antibody
Product Specific Notices for Mouse TGF-beta RI/ALK-5 Antibody
For research use only
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