MP1/MAP2K1IP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87837

Novus Biologicals, part of Bio-Techne
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NBP1-87837
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MP1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLPLVVSFIASSSANTGLIVSLEKELAPLFEELRQVVEVS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MP1/MAP2K1IP1 Antibody

Western Blot: MP1/MAP2K1IP1 Antibody [NBP1-87837]

Western Blot: MP1/MAP2K1IP1 Antibody [NBP1-87837]

Western Blot: MP1/MAP2K1IP1 Antibody [NBP1-87837] - Analysis in human cell line SK-MEL-30.
Immunohistochemistry: MP1/MAP2K1IP1 Antibody [NBP1-87837]

Immunohistochemistry: MP1/MAP2K1IP1 Antibody [NBP1-87837]

Immunohistochemistry: MP1/MAP2K1IP1 Antibody [NBP1-87837] - Staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.
Western Blot: MP1/MAP2K1IP1 Antibody [NBP1-87837]

Western Blot: MP1/MAP2K1IP1 Antibody [NBP1-87837]

Western Blot: MP1/MAP2K1IP1 Antibody [NBP1-87837] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: SK-MEL-30

Applications for MP1/MAP2K1IP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MP1

The function of MAP2K1IP1/MAPKSP1 (MP1;MEK partner-1) a 14kDa scaffold protein, is to bind specifically to MEK1 and ERK1 and bring them in close proximity in order to facilitate their activation. Localized to the late endosome, MAP2K1IP1 also interacts with an adaptor protein p14. While the interaction between MAPKSP1-ERK1 can take place in the absence of the adaptor protein p14, it is strengthened in the presence of p14. Additionally, it has been suggested that the binding of MAP2K1IP1/MAPKSP1 to MEK1 resides in a proline-rich sequence (residue 270-307) of MEK1.

Long Name

MEK-binding Protein 1

Alternate Names

LAMTOR3, MAP2K1IP1, Mapbp

Gene Symbol

LAMTOR3

Additional MP1 Products

Product Documents for MP1/MAP2K1IP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MP1/MAP2K1IP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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