MSPR/Ron Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88136

Novus Biologicals, part of Bio-Techne
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NBP1-88136
NBP1-88136-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MSPR/Ron Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EDPVVLSISPNCGYINSHITICGQHLTSAWHLVLSFHDGLRAVESRCERQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVPLKP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MSPR/Ron Antibody

Immunocytochemistry/ Immunofluorescence: MSPR/Ron Antibody [NBP1-88136]

Immunocytochemistry/ Immunofluorescence: MSPR/Ron Antibody [NBP1-88136]

Immunocytochemistry/Immunofluorescence: MSP R/Ron Antibody [NBP1-88136] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
Immunohistochemistry-Paraffin: MSPR/Ron Antibody [NBP1-88136]

Immunohistochemistry-Paraffin: MSPR/Ron Antibody [NBP1-88136]

Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88136] - Staining of human cerebral cortex.
Immunohistochemistry-Paraffin: MSPR/Ron Antibody [NBP1-88136]

Immunohistochemistry-Paraffin: MSPR/Ron Antibody [NBP1-88136]

Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88136] - Staining of human vagina shows strong cytoplasmic positivity in squamous epithelial cells.
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Applications for MSPR/Ron Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MSPR/Ron

Ron, the tyrosine kinase receptor for the Macrophage-stimulating protein, is involved in cell dissociation, motility, and matrix invasion (1). Ron, a cDNA homologous to the hepatocyte growth factor (HGF) receptor gene (MET), encodes a putative tyrosine kinase. It has been shown that the Ron gene is expressed in several epithelial tissues as well as in granulocytes and monocytes. The major RON transcript is translated into a glycosylated single chain precursor, cleaved into a 185 kDa heterodimer (p185Ron) of 35 (alpha) and 150 kDa (beta) disulfide-linked chains, before exposure at the cell surface (2).

Long Name

Macrophage Stimulating Protein Receptor

Alternate Names

CD136, MSP R, MST1R, Ron

Gene Symbol

MST1R

Additional MSPR/Ron Products

Product Documents for MSPR/Ron Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MSPR/Ron Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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