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MST1/STK4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB110-39128

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to the C-terminus of human Mammalian Sterile 20-like 1 (Serine/Threonine Kinase 4) using the numbering given in Swiss Prot entry Q13043 (GeneID 6789).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MST1/STK4 Antibody

Immunohistochemistry: STK4 Antibody [NB110-39128]

Immunohistochemistry: STK4 Antibody [NB110-39128]

Immunohistochemistry: STK4 Antibody [NB110-39128] - Sample: FFPE section of human placenta. Antibody: Affinity purified rabbit anti- MST1/2 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunoprecipitation: STK4 Antibody [NB110-39128]

Immunoprecipitation: STK4 Antibody [NB110-39128]

Immunoprecipitation: STK4 Antibody [NB110-39128] - Detection of MST1 and MST2 on HeLa whole cell lysate using NB110-39128. MST1 and MST2 were simultaneously IPed using other MST1/2 antibodies.

Applications for MST1/STK4 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:5000-1:15000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MST1/STK4

MST1 and MST2 are members of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST1 and MST2 are cleaved by caspase-3 and mediate apoptosis.

Long Name

Mammalian STE20-like Protein Kinase 1/Serine/Threonine Protein Kinase 4

Alternate Names

KRS2, STK4, YSK3

Entrez Gene IDs

6789 (Human); 58231 (Mouse)

Gene Symbol

STK4

UniProt

Additional MST1/STK4 Products

Product Documents for MST1/STK4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MST1/STK4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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