MTMR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33580

Novus Biologicals, part of Bio-Techne
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NBP2-33580
NBP2-33580-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MTMR2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: CESLGSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPDLRVLRESNKLAEMEEPPL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (86%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MTMR2 Antibody

Immunocytochemistry/ Immunofluorescence: MTMR2 Antibody [NBP2-33580]

Immunocytochemistry/ Immunofluorescence: MTMR2 Antibody [NBP2-33580]

Immunocytochemistry/Immunofluorescence: MTMR2 Antibody [NBP2-33580] - Staining of human cell line RT4 shows localization to vesicles.
Immunohistochemistry-Paraffin: MTMR2 Antibody [NBP2-33580]

Immunohistochemistry-Paraffin: MTMR2 Antibody [NBP2-33580]

Immunohistochemistry-Paraffin: MTMR2 Antibody [NBP2-33580] - Staining of human esophagus shows strong cytoplasmic positivity in squamous epithelial cells.

Applications for MTMR2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MTMR2

MTMR2 is a member of the myotubularin family and encodes a putative tyrosine phosphatase. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Multiple alternatively spliced transcript variants have been found for this gene, but the protein products of some of these variants are likely not viable, as they are nonsense-mediated mRNA decay (NMD) candidates.

Alternate Names

CMT4B, CMT4B1, EC 3.1.3, EC 3.1.3.2, EC 3.1.3.48, KIAA1073EC 3.1.3.-, myotubularin related protein 2, myotubularin-related protein 2

Gene Symbol

MTMR2

UniProt

Q13614 (Human)

Additional MTMR2 Products

Product Documents for MTMR2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MTMR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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