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Key Product Details

Species Reactivity

Human, Rat (Negative)

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # MUC6/916

Concentration

0.2 mg/ml

Product Specifications

Immunogen

Recombinant fragment covering tandem repeats of human MUC6 protein (exact sequence is proprietary) (Uniprot: Q6W4X9)

Reactivity Notes

Does not react with Rat.

Localization

Cytoplasmic & Secreted

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Theoretical MW

252 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-47799)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for MUC6 Antibody (MUC6/916)

Immunohistochemistry-Paraffin: MUC6 Antibody (MUC6/916) [NBP2-44376]

Immunohistochemistry-Paraffin: MUC6 Antibody (MUC6/916) [NBP2-44376]

Immunohistochemistry-Paraffin: MUC6 Antibody (MUC6/916) [NBP2-44376] - Human Gastric Carcinoma stained with MUC6 Monoclonal Antibody (MUC6/916).
Immunohistochemistry-Paraffin: MUC6 Antibody (MUC6/916) [NBP2-44376]

Immunohistochemistry-Paraffin: MUC6 Antibody (MUC6/916) [NBP2-44376]

Immunohistochemistry-Paraffin: MUC6 Antibody (MUC6/916) [NBP2-44376] - Human Gastric Carcinoma stained with MUC6 Monoclonal Antibody (MUC6/916).

Applications for MUC6 Antibody (MUC6/916)

Application
Recommended Usage

Immunohistochemistry-Paraffin

2-4 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 2-4ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: MUC6

Mucin is a high M.W. (>1,000 kDa) glycoprotein, expressed by mucus cells of the gastric epithelium and by goblet cells of the fetal, precancerous and cancerous colon, but not by those of the normal colon. It also appears in other epithelial tissues, which are embryologically derived from the foregut (epigastric and bronchial epithelium) and in M ller ducts (mucus cells of the endocervix and urethral epithelium near the prostatic utriculus).

Alternate Names

gastric mucin, Gastric mucin-6, MUC-6, mucin 6, gastric, mucin 6, oligomeric mucus/gel-forming, mucin-6

Gene Symbol

MUC6

UniProt

Additional MUC6 Products

Product Documents for MUC6 Antibody (MUC6/916)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MUC6 Antibody (MUC6/916)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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