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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # MTA30 2G10/3

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Human MUS81

Localization

Nuclear

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Mus81 Antibody (MTA30 2G10/3) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:10 - 1:1000

Immunocytochemistry/ Immunofluorescence

1:10 - 1:500

Immunohistochemistry

1:10 - 1:500

Immunoprecipitation

1:10 - 1:500

Western Blot

1:1000
Application Notes
MTA30 2G10/3 is recommended for WB of recombinant protein, human whole cell extracts, native IP and fractionated cell extracts at a concentration of 1:1000. This antibody is CyTOF ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mus81

Mus81 and EME1 constitute a heterodimeric endonuclease that has been implicated in mitotic and meiotic recombination in eukaryotes. Reduction or loss of a protein called Mus81 can led to the development of lymphomas and other tumours in mice. Mus81 is a protein long thought to be involved in repairing DNA that is damaged during normal metabolic processes.

Alternate Names

crossover junction endonuclease MUS81, EC 3.1.22, EC 3.1.22.-, FLJ21012, FLJ44872, MUS81 endonuclease homolog (S. cerevisiae), MUS81 endonuclease homolog (yeast), SLX3, SLX3 structure-specific endonuclease subunit homolog

Entrez Gene IDs

80198 (Human)

Gene Symbol

MUS81

Additional Mus81 Products

Product Documents for Mus81 Antibody (MTA30 2G10/3) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mus81 Antibody (MTA30 2G10/3) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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