Musashi-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21216

Novus Biologicals, part of Bio-Techne
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NBP3-21216-100ul
NBP3-21216-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Musashi-1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Musashi-1 Antibody

Immunohistochemistry-Paraffin: Musashi-1 Antibody [NBP3-21216] -

Immunohistochemistry-Paraffin: Musashi-1 Antibody [NBP3-21216] -

Staining of human retina shows strong nuclear and cytoplasmic positivity in inner nuclear and ganglion cell layers.
Immunocytochemistry/Immunofluorescence: Musashi-1 Antibody [NBP3-21216] -

Immunocytochemistry/Immunofluorescence: Musashi-1 Antibody [NBP3-21216] -

Staining of human cell line SH-SY5Y shows localization to nucleoplasm & cytosol.

Applications for Musashi-1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100. For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Musashi-1

Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia. It may play a role in the pathogenesis of various neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play be an vital role in the development of several types of carcinoma such as human hepatoma, and may be a useful molecular marker for tumor detection.

Alternate Names

MSI1, Musashi1

Gene Symbol

MSI1

Additional Musashi-1 Products

Product Documents for Musashi-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Musashi-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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