Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87547

Novus Biologicals, part of Bio-Techne
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NBP1-87547
NBP1-87547-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CHRM3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPLGGHTVWQV

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 24658304).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP1-87547]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP1-87547]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP1-87547] - Staining of human cerebral cortex shows moderate positivity in neuronal processes.
Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP1-87547]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP1-87547]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP1-87547] - Staining of human prostate shows moderate to strong membranous and cytoplasmic positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP1-87547]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP1-87547]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP1-87547] - Staining of human lymph node shows low positivity in non-germinal center cells as expected.
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Applications for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
IHC, WB reported in scientific literature (PMID: 24658304). For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHRM3

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.

Long Name

Cholinergic Receptor Muscarinic 3

Alternate Names

HM3, mAChR M3

Gene Symbol

CHRM3

Additional CHRM3 Products

Product Documents for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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