MVK Antibody (2C5)

Novus Biologicals, part of Bio-Techne | Catalog # H00004598-M02

Novus Biologicals, part of Bio-Techne
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H00004598-M02
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2C5

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MVK Antibodies »

Product Specifications

Immunogen

MVK (AAH16140, 297 a.a. ~ 396 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Specificity

MVK - mevalonate kinase (mevalonic aciduria) (2C5)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for MVK Antibody (2C5)

Western Blot: MVK Antibody (2C5) [H00004598-M02]

Western Blot: MVK Antibody (2C5) [H00004598-M02]

Western Blot: MVK Antibody (2C5) [H00004598-M02] - Analysis of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.Lane 1: MVK transfected lysate(42.451 KDa).Lane 2: Non-transfected lysate.
Immunohistochemistry-Paraffin: MVK Antibody (2C5) [H00004598-M02]

Immunohistochemistry-Paraffin: MVK Antibody (2C5) [H00004598-M02]

Immunohistochemistry-Paraffin: MVK Antibody (2C5) [H00004598-M02] - Analysis of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. Antibody concentration 3 ug/ml.
Sandwich ELISA: MVK Antibody (2C5) [H00004598-M02] - Detection limit for recombinant GST tagged MVK is approximately 3ng/ml as a capture antibody.

Applications for MVK Antibody (2C5)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MVK

This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq]

Long Name

Mevalonate Kinase

Alternate Names

LRBP, Mevalonic Aciduria, MVLK, POROK3

Entrez Gene IDs

4598 (Human)

Gene Symbol

MVK

UniProt

AAH16140 (Human)

Additional MVK Products

Product Documents for MVK Antibody (2C5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MVK Antibody (2C5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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