MVK Antibody (OTI 1D7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-00775

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI 1D7

Concentration

1 mg/ml

View all MVK Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human MVK (NP_000422) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

42.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MVK Antibody (OTI 1D7)

Western Blot: MVK Antibody (OTI 1D7) [NBP2-00775]

Western Blot: MVK Antibody (OTI 1D7) [NBP2-00775]

Western Blot: MVK Antibody (OTI 1D7) [NBP2-00775] - Analysis of extracts (35ug) from 9 different cell lines by using anti-MVK monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Immunocytochemistry/ Immunofluorescence: MVK Antibody (OTI 1D7) [NBP2-00775]

Immunocytochemistry/ Immunofluorescence: MVK Antibody (OTI 1D7) [NBP2-00775]

Immunocytochemistry/Immunofluorescence: MVK Antibody (OTI 1D7) [NBP2-00775] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY MVK.
Western Blot: MVK Antibody (OTI 1D7) [NBP2-00775]

Western Blot: MVK Antibody (OTI 1D7) [NBP2-00775]

Western Blot: MVK Antibody (OTI 1D7) [NBP2-00775] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MVK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MVK.

Applications for MVK Antibody (OTI 1D7)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MVK

This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq].

Long Name

Mevalonate Kinase

Alternate Names

LRBP, Mevalonic Aciduria, MVLK, POROK3

Entrez Gene IDs

4598 (Human)

Gene Symbol

MVK

Additional MVK Products

Product Documents for MVK Antibody (OTI 1D7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MVK Antibody (OTI 1D7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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