MyD88 Antibody (RM306)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61565

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM306

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MyD88 Antibodies »

Product Specifications

Immunogen

A peptide corresponding to the N-terminus of Human MyD88

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MyD88 Antibody (RM306)

Western Blot: MyD88 Antibody (RM306) [NBP2-61565]

Western Blot: MyD88 Antibody (RM306) [NBP2-61565]

Western Blot: MyD88 Antibody (RM306) [NBP2-61565] - Western Blot of K562 cells lysate using NBP2-61565.
Immunohistochemistry-Paraffin: MyD88 Antibody (RM306) [NBP2-61565]

Immunohistochemistry-Paraffin: MyD88 Antibody (RM306) [NBP2-61565]

Immunohistochemistry-Paraffin: MyD88 Antibody (RM306) [NBP2-61565] - Immunohistochemical staining of formalin fixed and paraffin embedded human kidney tissue section using NBP2-61565.

Applications for MyD88 Antibody (RM306)

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:250

Immunohistochemistry-Paraffin

1:100-1:250

Western Blot

1:100-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MyD88

Myeloid differentiation Marker 88 (MyD88) is a universal adaptor molecule for the Toll/IL1R and is involved in the inflammatory response induced by IL1, IL18 and LPS. MyD88 associates with and recruits IRAK to IL1 receptor complex in response to IL1. This pathway further leads to activation of NFkB. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL1 and IL18, and MyD88 deficient mice lack responses to bacterial product LPS that employs Toll like receptors 2 and 4 as the signaling receptors.

Long Name

Myeloid Differentiation Primary Response Gene 88

Alternate Names

MYD88D, myeloid differentiation primary response gene (88), myeloid differentiation primary response protein MyD88

Gene Symbol

MYD88

Additional MyD88 Products

Product Documents for MyD88 Antibody (RM306)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MyD88 Antibody (RM306)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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