MyD88 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24671

Novus Biologicals, part of Bio-Techne
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NBP2-24671
NBP2-24671SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Canine (94%), Chimpanzee (94%), Equine (94%), Opossum (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all MyD88 Antibodies »

Product Specifications

Immunogen

A portion of amino acids 50-100 of human MyD88 was used as immunogen for this antibody.

Reactivity Notes

The amino acid sequence used as immunogen is 88% homologous in rat.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MyD88 Antibody

Western Blot: MyD88 Antibody [NBP2-24671]

Western Blot: MyD88 Antibody [NBP2-24671]

Western Blot: MyD88 Antibody [NBP2-24671] - Analysis of MyD88 using MyD88 antibody. Human Ramos cell lysate probed using MyD88 antibody at 4 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for MyD88 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

reported in scientific literature (PMID 20228254)

Western Blot

2-4 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MyD88

Myeloid differentiation Marker 88 (MyD88) is a universal adaptor molecule for the Toll/IL1R and is involved in the inflammatory response induced by IL1, IL18 and LPS. MyD88 associates with and recruits IRAK to IL1 receptor complex in response to IL1. This pathway further leads to activation of NFkB. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL1 and IL18, and MyD88 deficient mice lack responses to bacterial product LPS that employs Toll like receptors 2 and 4 as the signaling receptors.

Long Name

Myeloid Differentiation Primary Response Gene 88

Alternate Names

MYD88D, myeloid differentiation primary response gene (88), myeloid differentiation primary response protein MyD88

Gene Symbol

MYD88

Additional MyD88 Products

Product Documents for MyD88 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MyD88 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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