Myelin PLP Antibody (2D7)

Novus Biologicals, part of Bio-Techne | Catalog # H00005354-M03

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
H00005354-M03
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2D7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Myelin PLP Antibodies »

Product Specifications

Immunogen

PLP1 (NP_000524, 177 a.a. ~ 232 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. YFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAE

Specificity

PLP1 - proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) (2D7)

Marker

Oligodendrocyte Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Myelin PLP Antibody (2D7)

Immunocytochemistry/ Immunofluorescence: Myelin PLP Antibody (2D7) [H00005354-M03]

Immunocytochemistry/ Immunofluorescence: Myelin PLP Antibody (2D7) [H00005354-M03]

Immunocytochemistry/Immunofluorescence: Myelin PLP Antibody (2D7) [H00005354-M03] - Analysis of monoclonal antibody to PLP1 on HeLa cell. Antibody concentration 10 ug/ml
ELISA: Myelin PLP Antibody (2D7) [H00005354-M03]

ELISA: Myelin PLP Antibody (2D7) [H00005354-M03]

ELISA: Myelin PLP Antibody (2D7) [H00005354-M03] - Detection limit for recombinant GST tagged PLP1 is approximately 0.1ng/ml as a capture antibody.

Applications for Myelin PLP Antibody (2D7)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

10 ug/ml

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Myelin PLP

This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq]

Long Name

Proteolipid Protein

Alternate Names

DM-20, Lipophilin, MMPL, PLP1, SPG2

Entrez Gene IDs

5354 (Human)

Gene Symbol

PLP1

UniProt

NP_000524 (Human)

Additional Myelin PLP Products

Product Documents for Myelin PLP Antibody (2D7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Myelin PLP Antibody (2D7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.