Myocilin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89769

Novus Biologicals, part of Bio-Techne
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NBP1-89769
NBP1-89769-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Myocilin Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRIL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Myocilin Antibody

Western Blot: Myocilin Antibody [NBP1-89769]

Western Blot: Myocilin Antibody [NBP1-89769]

Western Blot: Myocilin Antibody [NBP1-89769] - Analysis in human adipose tissue .
Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-89769]

Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-89769]

Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-89769] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-89769]

Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-89769]

Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-89769] - Staining of human gastrointestinal shows strong cytoplasmic granular positivity in glandular cells.
View 1 more images

Applications for Myocilin Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Myocilin

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Alternate Names

GLC1A, MYOC, TIGR

Gene Symbol

MYOC

Additional Myocilin Products

Product Documents for Myocilin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Myocilin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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