MyoD Antibody (MYD712)

Validated:

Cited:

Validated:

Cited:

Unconjugated

Monoclonal Mouse IgG₁ kappa Clone # MYD712

0.2 mg/ml

Recombinant human MyoD1 protein

Nuclear. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.

Recognizes a phosphor-protein of 45kDa, identified as MyoD1. This MAb does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas.

Rhabdomyosarcoma Marker

Monoclonal

Mouse

IgG₁ kappa

45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein A purified

PBS with 0.05% BSA.

0.05% Sodium Azide

0.2 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C.