NAT1 Antibody (SR4177)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27820

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27820-100ul
NBP3-27820-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR4177

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NAT1 Antibodies »

Product Summary for NAT1 Antibody (SR4177)

Immunogen

A synthesized peptide derived from human NAT1 (Uniprot #: P18440)

Specificity

Detects endogenous levels of total NAT1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

30 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NAT1 Antibody (SR4177)

Western Blot: NAT1 Antibody (SR4177) [NBP3-27820] -

Western Blot: NAT1 Antibody (SR4177) [NBP3-27820] - Western blot analysis of NAT1 expression in LnCaP cell lysate.

Applications for NAT1 Antibody (SR4177)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NAT1

NAT1 is a gene that codes for a protein that helps in the detoxification of various hydrazine and arylamine drugs as well as to bioactivate several carcinogens and is 290 amino acids long with a weight of approximately 34 kDa. Current studies are being done on several diseases and disorders related to this gene including neural tube defect, drug-induced hepatitis, talipes equinovarus, spina bifida, multiple chemical sensitivity, malignant pleural mesothelioma, non-Hodgkin lymphoma, cleft palate, familial adenomatous polyposis, substance abuse, orofacial cleft, peptic ulcer, lymphoblastic leukemia, systemic lupus erythematosus, cystic fibrosis, lupus erythematosus, Hodgkin's lymphoma, inflammatory bowel disease, and motor neuron disease. NAT1 has also been shown to have interactions with NAA10, SNTA1, SYP1A2, CYP2A6, and XDH in pathways such as the arylamine metabolism, acetylation, and drug metabolism pathways.

Alternate Names

AAC1N-acetyltransferase type 1, Arylamide acetylase 1, arylamine N-acetyltransferase 1, EC 2.3.1.5, MNAT, Monomorphic arylamine N-acetyltransferase, N-acetyltransferase 1 (arylamine N-acetyltransferase), NAT-1, NATI

Gene Symbol

NAT1

Additional NAT1 Products

Product Documents for NAT1 Antibody (SR4177)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NAT1 Antibody (SR4177)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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