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NAT10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-06055

Novus Biologicals, part of Bio-Techne
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NBP1-06055

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-KSDKKRKLEAKQ corresponding to internal region (near C-Terminus) according to NP_078938.1.

Epitope

C-KSDKKRKLEAKQ

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for NAT10 Antibody

Immunohistochemistry-Paraffin: NAT10 Antibody [NBP1-06055]

Immunohistochemistry-Paraffin: NAT10 Antibody [NBP1-06055]

Immunohistochemistry-Paraffin: NAT10 Antibody [NBP1-06055] - (3.8ug/ml) staining of paraffin embedded Human Colon. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for NAT10 Antibody

Application
Recommended Usage

Immunohistochemistry

3 - 6 ug/ml

Immunohistochemistry-Paraffin

3 - 6 ug/ml

Peptide ELISA

Detection limit 1:64000
Application Notes
WB: Preliminary experiments gave an approx. 26 kDa band in human brain (cerebellum, frontal cortex and hippocampus) lysates after 0.01 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 116 kDa band according to NP_078938.1. The 26 kDa band was successfully blocked by incubation with the immunizing peptide. IHC-P: Human colon shows nuclear staining in absorptive cells.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NAT10

NAT10 has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, a

Long Name

RNA cytidine acetyltransferase

Alternate Names

ALP, EC 2.3.1.-, hALP, KIAA1709

Entrez Gene IDs

55226 (Human); 98956 (Mouse)

Gene Symbol

NAT10

Additional NAT10 Products

Product Documents for NAT10 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NAT10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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