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Nav1.5 Antibody (4G8:1G7)

Novus Biologicals, part of Bio-Techne | Catalog # NB110-61010

Novus Biologicals, part of Bio-Techne
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NB110-61010-0.025mg
NB110-61010

Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Radioimmunoassay, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgM Clone # 4G8:1G7

Concentration

1 mg/ml

Product Specifications

Immunogen

Peptide (14mer) from an extracellular domain of Nav1.5 - VSENIKLGNLSALR

Clonality

Monoclonal

Host

Mouse

Isotype

IgM

Applications for Nav1.5 Antibody (4G8:1G7)

Application
Recommended Usage

Flow Cytometry

1:10 - 1:1000

Immunocytochemistry/ Immunofluorescence

10 ug/ml

Immunohistochemistry

1:10 - 1:500

Immunoprecipitation

1:10 - 1:500

Radioimmunoassay

1:100 - 1:2000

Western Blot

2 ug/ml
Application Notes
This antibody is CyTOF ready. Positive control(s): Cell lines over expressing Nav1.5, e.g Nav 1.5-HEK293 cells

Formulation, Preparation, and Storage

Purification

Thiophilic Chromatography

Formulation

PBS

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Nav1.5

Voltage-gated sodium channesl (VGSCs) mediate regenerative cell membrane depolarization and conduction of electrical signaling in nerves and muscles. Expression is also detected in lymphocytes, glia, and fibroblasts. VGSC proteins are comprised of a core alpha-subunit, together with one or more additional regulatory beta-subunit. Expression has been detected in a number of tumor cell lines and has been implicated in the metastatic behavior of breast and prostate cancer cells.

Long Name

Sodium channel protein type 5 subunit alpha

Alternate Names

SCN5A

Entrez Gene IDs

6331 (Human)

Gene Symbol

SCN5A

Additional Nav1.5 Products

Product Documents for Nav1.5 Antibody (4G8:1G7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Nav1.5 Antibody (4G8:1G7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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