Nectin-4/PVRL4 Antibody (6D3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26115

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26115-100ul
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Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # 6D3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Nectin-4 Antibodies »

Product Specifications

Immunogen

Recombinant Human Nectin-4/PVRL4 protein [UniProt Q96NY8]

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Scientific Data Images for Nectin-4/PVRL4 Antibody (6D3)

Nectin-4/PVRL4 Antibody (6D3)

ELISA: Nectin-4/PVRL4 Antibody (6D3) [NBP3-26115] -

ELISA: Nectin-4/PVRL4 Antibody (6D3) [NBP3-26115] - The Binding Activity of Nectin-4/PVRL4 with Nectin-4/PVRL4 Antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human Nectin-4/PVRL4 at 2 ug/mL can bind Nectin-4/PVRL4 Antibody, the EC50 is 0.6029-0.7837 ng/mL.

Applications for Nectin-4/PVRL4 Antibody (6D3)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50% Glycerol, 0.01M PBS, PH 7.4

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Nectin-4

PVRL4, also known as Poliovirus receptor-related protein 4, is a 510 amino acid protein that is 55 kDa, predominantly expressed in placenta and breast carcinoma, is a single-pass type I membrane protein involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1, and oes not act as receptor for alpha-herpesvirus entry into cells. Disease research is being performed in relation to this protein and ectodermal dysplasia, syndactyly, ectodermal dysplasia-syndactyly syndrome 1, measles, ovarian cancer, breast carcinoma, lung cancer, and carcinoma. The PVRL4 protein has shown an interaction with PVRL1, MLLT4, PICK1, TIGIT, PARD3, PVRL3, and PVRL2 in Adherens junctions interactions, Nectin/Necl trans heterodimerization, Cell junction organization, Cell-Cell communication, Cell-cell junction organization, Sertoli-Sertoli Cell Junction Dynamics, and Epithelial Adherens Junctions pathways.

Long Name

Poliovirus Receptor Related 4

Alternate Names

LNIR, Nectin4, PRR4, PVRL4

Gene Symbol

NECTIN4

Additional Nectin-4 Products

Product Documents for Nectin-4/PVRL4 Antibody (6D3)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Nectin-4/PVRL4 Antibody (6D3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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