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NEU-1/Sialidase-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-69387

Novus Biologicals, part of Bio-Techne
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NBP1-69387

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to NEU1(sialidase 1 (lysosomal sialidase)) The peptide sequence was selected from the middle region of NEU1. Peptide sequence VWSKDDGVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHG. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for NEU-1/Sialidase-1 Antibody

Western Blot: NEU-1/Sialidase-1 Antibody [NBP1-69387]

Western Blot: NEU-1/Sialidase-1 Antibody [NBP1-69387]

Western Blot: NEU-1/Sialidase-1 Antibody [NBP1-69387] - This Anti-NEU1 antibody was used in Western Blot of Fetal Pancreas tissue lysate at a concentration of 5ug/ml.
Immunohistochemistry: NEU-1/Sialidase-1 Antibody [NBP1-69387]

Immunohistochemistry: NEU-1/Sialidase-1 Antibody [NBP1-69387]

Immunohistochemistry: NEU-1/Sialidase-1 Antibody [NBP1-69387] - Human Muscle

Applications for NEU-1/Sialidase-1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NEU-1/Sialidase-1

NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.

Long Name

N-acetyl-alpha-Neuraminidase 1

Alternate Names

NEU1, Sialidase-1

Gene Symbol

NEU1

UniProt

Additional NEU-1/Sialidase-1 Products

Product Documents for NEU-1/Sialidase-1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NEU-1/Sialidase-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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