Neuregulin-1/NRG1 Antibody (MM0483-1Y45) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-11811

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0483-1Y45

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all Neuregulin-1/NRG1 Antibodies »

Product Specifications

Immunogen

Human recombinant Neuregulin-1/NRG1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Scientific Data Images for Neuregulin-1/NRG1 Antibody (MM0483-1Y45) - Azide and BSA Free

Immunohistochemistry-Paraffin: Neuregulin-1/NRG1 Antibody (MM0483-1Y45) - Azide and BSA Free [NBP2-11811]

Immunohistochemistry-Paraffin: Neuregulin-1/NRG1 Antibody (MM0483-1Y45) - Azide and BSA Free [NBP2-11811]

Immunohistochemistry-Paraffin: Neuregulin-1/NRG1 Antibody (MM0483-1Y45) [NBP2-11811] - 10% Buffer formalin fixed and parffine embedded human placetal tissue section (4um) is subjected IHC staining using NBP2-11811. Tissue section was pretreated in citric buffer (pH 6.0) with microwave for antige retrieval before IHC is applied.

Applications for Neuregulin-1/NRG1 Antibody (MM0483-1Y45) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Neuregulin-1/NRG1

Neuregulin 1 (NRG1, isoform HRG-beta2) belongs to the neuregulin/heregulin cytokine family consisting of variants of the four genes NRG1, NRG2, NRG3 and NRG4. More than 15 transmembrane and secreted protein isoforms exist for NRG1, they are generated by alternative promoter usage and mRNA splicing. The different isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. The EGF-like domain interacts with ErbB3 and ErbB4 tyrosine kinase receptors, resulting in tyrosine phosphorylation and NRG1 signaling. NRG proteins show distinct spatial and temporal expression patterns. These proteins are important for the development of the nervous system and the heart and in the regulation of neurotransmission.

Alternate Names

Heregulin-1, HGL, HRG1-alpha, HRG1-beta 1, Neuregulin1, NRG1

Gene Symbol

NRG1

UniProt

AAA58639 (Human)

Additional Neuregulin-1/NRG1 Products

Product Documents for Neuregulin-1/NRG1 Antibody (MM0483-1Y45) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Neuregulin-1/NRG1 Antibody (MM0483-1Y45) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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