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Neuregulin-2 Antibody (3D2)

Novus Biologicals, part of Bio-Techne | Catalog # H00009542-M01

Novus Biologicals, part of Bio-Techne
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H00009542-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 3D2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

NRG2 (NP_004874, 116 a.a. ~ 215 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SLKSVQDQAYKAPVVVEGKVQGLVPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCVPLERNQRYIFFLEPTEQPLVFKTAFAPLD

Reactivity Notes

Other species not tested.

Specificity

NRG2 - neuregulin 2

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for Neuregulin-2 Antibody (3D2)

Western Blot: Neuregulin-2 Antibody (3D2) [H00009542-M01]

Western Blot: Neuregulin-2 Antibody (3D2) [H00009542-M01]

Western Blot: Neuregulin-2 Antibody (3D2) [H00009542-M01] - NRG2 monoclonal antibody (M01), clone 3D2. Analysis of NRG2 expression in human pancreas.
ELISA: Neuregulin-2 Antibody (3D2) [H00009542-M01]

ELISA: Neuregulin-2 Antibody (3D2) [H00009542-M01]

ELISA: Neuregulin-2 Antibody (3D2) [H00009542-M01] - Detection limit for recombinant GST tagged NRG2 is approximately 0.03ng/ml as a capture antibody.

Applications for Neuregulin-2 Antibody (3D2)

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Neuregulin-2/NRG2

Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcripts encoding distinct isoforms have been described.

Alternate Names

Don-1, Neuregulin2, NRG2, NTAK

Entrez Gene IDs

9542 (Human)

Gene Symbol

NRG2

OMIM

603818 (Human)

Additional Neuregulin-2/NRG2 Products

Product Documents for Neuregulin-2 Antibody (3D2)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Neuregulin-2 Antibody (3D2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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