Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # S110-29

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Neuroligin 3/NLGN3 Antibodies »

Product Specifications

Immunogen

Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2.

Reactivity Notes

Immunogen displays sequence identity for non-tested species: Human and Mouse.

Localization

Cell Membrane , Cell Junction , Synapse

Specificity

Approx 60% identity with Neuroligin-1. approx 40% identity with Neuroligin-2.Detects approx 110kDa. Does not cross-react with Neuroligin-1, -2, -4 or -4.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Neuroligin 3/NLGN3 Antibody (S110-29) [DyLight 488]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Neuroligin 3/NLGN3

Neuroligin 3 encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but their full length sequences have not been determined.

Alternate Names

ASPGX1, AUTSX1, HNL3, NL3, NLGN3

Gene Symbol

NLGN3

Additional Neuroligin 3/NLGN3 Products

Product Documents for Neuroligin 3/NLGN3 Antibody (S110-29) [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Neuroligin 3/NLGN3 Antibody (S110-29) [DyLight 488]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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