NFkB1/NFkB p105 Antibody [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77395CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-77395AF350

Alexa Fluor 405

NBP1-77395AF405

Alexa Fluor 488

NBP1-77395AF488

Alexa Fluor 532

NBP1-77395AF532

Alexa Fluor 594

NBP1-77395AF594

Alexa Fluor 647

NBP1-77395AF647

Alexa Fluor 700

NBP1-77395AF700

Alexa Fluor 750

NBP1-77395AF750

Allophycocyanin

NBP1-77395APC

Biotin

NBP1-77395B

DyLight 350

NBP1-77395UV

DyLight 405

NBP1-77395V

DyLight 488

NBP1-77395G

DyLight 550

NBP1-77395R

DyLight 594

NBP1-77395DL594

DyLight 650

NBP1-77395C

DyLight 680

NBP1-77395FR

DyLight 755

NBP1-77395IR

FITC

NBP1-77395F

HRP

NBP1-77395H

Janelia Fluor 525

NBP1-77395JF525

Janelia Fluor 549

NBP1-77395JF549

Janelia Fluor 646

NBP1-77395JF646

Janelia Fluor 669

NBP1-77395JF669

mFluor Violet 450 SE

NBP1-77395MFV450

mFluor Violet 500 SE

NBP1-77395MFV500

mFluor Violet 610 SE

NBP1-77395MFV610

PE

NBP1-77395PE

PerCP

NBP1-77395PCP

Forumulation

Catalog #

BSA Free

NBP1-77395

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Simple Western, Western Blot

Label

CoraFluor 1

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NFkB1 Antibodies »

Product Specifications

Immunogen

A genomic peptide made to an N-terminal region of the human NFkB p105/p50 protein (within residues 400-590). [Swiss-Prot P19838]

Localization

Nucleus and cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for NFkB1/NFkB p105 Antibody [CoraFluor™ 1]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Simple Western

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: NFkB1

Nuclear factor kappa beta (NFKB) is a transcription factor that is highly influenced by stress, free-radicals, UV light and hypoxia. Unsurprisingly, NFKB is essential for many human cancers, as it regulates the expression of many downstream proteins that regulate or modify cellular growth and development. NFKB effects on angiogenic pathways and reactive mechanisms to stress and damage are well established throughout literature. Atherosclerosis is partly attributed to the mis-regulation of NFKB in hypoxia. Arthritis is related to inflammation proteins regulated through NFKB. It also has been shown to be important in synapses in brain, leading to memory and cognitive ability or impairment. In all, NFKB is one of the fastest responding transcription factors in humans, and is likely to mediate many responsive events in diseases and injury recovery.

Long Name

Nuclear Factor Kappa-B, Subunit 1

Alternate Names

NF-kB1

Gene Symbol

NFKB1

Additional NFkB1 Products

Product Documents for NFkB1/NFkB p105 Antibody [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for NFkB1/NFkB p105 Antibody [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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