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Niemann-Pick type C2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15044

Novus Biologicals, part of Bio-Techne
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NBP2-15044

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (100%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Niemann-Pick type C2 Antibody

Immunogen

Full length human Niemann-Pick type C2 Recombinant protein.

Reactivity Notes

Chimpanzee (100%), Mouse (81%), Rat (80%), Dog (80%), Pig (85%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

17 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Niemann-Pick type C2 Antibody

Western Blot: Niemann-Pick type C2 Antibody [NBP2-15044]

Western Blot: Niemann-Pick type C2 Antibody [NBP2-15044]

Western Blot: Niemann-Pick type C2 Antibody [NBP2-15044] - Sample (30 ug of whole cell lysate) A: HeLa 15% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: Niemann-Pick type C2 Antibody [NBP2-15044]

Immunohistochemistry-Paraffin: Niemann-Pick type C2 Antibody [NBP2-15044]

Immunohistochemistry-Paraffin: Niemann-Pick type C2 Antibody [NBP2-15044] - Protein at cytoplasm on lung carcinoma dilution: 1:250.

Applications for Niemann-Pick type C2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Niemann-Pick Type C2/NPC2

This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq]

Alternate Names

EDDM1, Epididymal Protein 1, HE1, NiemannPick Type C2, NPC2

Gene Symbol

NPC2

UniProt

Additional Niemann-Pick Type C2/NPC2 Products

Product Documents for Niemann-Pick type C2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Niemann-Pick type C2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.