The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Long Name

Neurokinin-3 Receptor

Alternate Names

Neurokinin B Receptor, Neuromedin-K Receptor, TAC3RL, TACR3

Gene Symbol

TACR3

Additional NK3R/TACR3 Products

Product Documents for NK3R/TACR3/Neurokinin B Receptor Antibody [PerCP]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for NK3R/TACR3/Neurokinin B Receptor Antibody [PerCP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

NK3R/TACR3/Neurokinin B Receptor Antibody [PerCP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06055PCP

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all NK3R/TACR3 Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Applications for NK3R/TACR3/Neurokinin B Receptor Antibody [PerCP]

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: NK3R/TACR3