NKG2E/KLRC3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46867

Novus Biologicals, part of Bio-Techne
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NBP2-46867
NBP2-46867-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NKG2E Antibodies »

Product Summary for NKG2E/KLRC3 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NKG2E/KLRC3 Antibody

Immunohistochemistry: NKG2E/KLRC3 Antibody [NBP2-46867]

Immunohistochemistry: NKG2E/KLRC3 Antibody [NBP2-46867]

Immunohistochemistry: NKG2E/KLRC3 Antibody [NBP2-46867] - Staining of human tonsil shows strong positivity in a subset of cells.

Applications for NKG2E/KLRC3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NKG2E

KLRC3 codes for a protein that works as a receptor for the recognition of MHC molecules by natural killers, and in some cases cytotoxic T-cells. KLRC3 is a gene made up of two isoforms, measuring 240 and 257 amino acids in length, and weighing approximately 27 and 29 kDa respectively. Studies have been done on diseases and disorders relating to this gene including monkeypox. KLRC3 has also been shown to have interactions with KLRD1, TYROBP, HLA-A, and HLA-C in pathways such as the antigen processing and natural killer cell mediated cytotoxicity pathways.

Long Name

Natural Killer G2E

Alternate Names

killer cell lectin-like receptor subfamily C, member 3, NK cell receptor E, NKG2-E type II integral membrane protein, NKG2-E-activating NK receptor, NKG2ENKG2-E

Entrez Gene IDs

3823 (Human)

Gene Symbol

KLRC3

UniProt

Q07444

Additional NKG2E Products

Product Documents for NKG2E/KLRC3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NKG2E/KLRC3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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